Renato's journey began in the late 1960s when he started collecting works by artists who were then relatively unknown, including Cy Twombly, Lucio Fontana, and Piero Manzoni. His foresight in identifying significant talents led to the formation of a distinguished collection that embraced movements like Arte Povera and Spatialism. With an unwavering passion for art, Renato became a key figure in promoting and nurturing emerging artists, playing a crucial role in launching many of their careers. His dedication established the gallery as a vital platform for artistic exploration and innovation. 

As Galleria Cardi gained recognition, it expanded its influence beyond Italy. Renato’s commitment to art extended through his innovative approach to exhibitions and collaborations with international critics. The gallery's reputation grew as it hosted significant shows and produced scholarly catalogues and monographs. These efforts attracted global attention and positioned Cardi Gallery as a critical player in the art world.